There has been an upsurge of questions posed to our health professionals about the benefits of milk thistle protection for patients who are at risk of cocaine toxicity. These questions are coming mainly from healthcare professionals but also some patients who have family members at risk. Our group of healthcare professionals at Just Health Experts reviewed the article, which was published in Journal of Molecular Medicine Reports (https://www.ncbi.nlm.nih.gov/pubmed/25174449), entitled, Milk thistle seed extract protects rat C6 astroglial cells from acute cocaine toxicity, to determine if the study can be used as a guide in clinical recommendations. A brief overview of milk thistle protection against cocaine toxicity is provided below.
Cocaine is a powerfully addictive and illegal drug, which widely abused in most countries around the world. It quickly works on the central nervous system (CNS) which leads to euphoria as well as cellular toxicity. In the study, milk thistle seed extract against cocaine toxicity in living shrimp larvae in the laboratory. Exposure to cocaine disrupted the architecture of the astroglial cells which resulted in less glutathione (GSH) level. The results showed that astroglial cells are more sensitive to cocaine than liver, kidney cells or larvae. The results of this study show that enhanced GSH can protect cells and show that compounds that promote GSH synthesis may be beneficial against cocaine toxicity. The study which shows some merit as it is the first of its kind. It is extremely difficult to understand, contains too much molecular detail, but shows some credible evidence for use as protection against acute cocaine toxicity.
The researchers and live chat with doctor facility at Just Health Experts determined that the study can serve as the basis for further animal testing as well as human.
If you would have any further questions about whether milk thistle can be used against acute cocaine toxicity in humans, please ask your healthcare professional or live chat with doctor at www.justhealthexperts.com. Milk thistle can be associated with several side effects and several potentially serious drug interactions. Some side effects reported with milk thistle include a headache, nausea, vomiting, and feeling jittery and sluggish.